Full Catalog

GPCRs

Receptor FamilyReceptorSpeciesParentalStable Cell Lines Division-Arrested Cells Membranes
AdenosineA1humanHEK293TC1427BDC1427BMC1427B
A1humanCHO-K1C1427-1DC1427-1MC1427-1
A2AhumanHEK293TC1428DC1428MC1428
A2AhumanCHO-K1C1428-1DC1428-1MC1428-1
A2AmouseHEK293TCm1428ADCm1428AMCm1428A
A2AmouseHEK293TCm1428BDCm1428BMCm1428B
A2AmouseCHO-K1Cm1428-1DCm1428-1MCm1428-1
A2BhumanHEK293TC1429DC1429MC1429
A2BhumanCHO-K1C1429-1DC1429-1MC1429-1
A2BhumanHEK293TC1429aDC1429aMC1429a
A2BratHEK293TCr1429DCr1429MCr1429
A3humanHEK293TC1430DC1430MC1430
A3humanCHO-K1C1430-1DC1430-1MC1430-1
Adhesion Class GPCRsGPR97humanHEK293TC1396DC1396MC1396
GPR110humanHEK293TC1378DC1378MC1378
Adrenergicalpha1AhumanCHO-K1C1431-1DC1431-1MC1431-1
alpha1BhumanCHO-K1C1432-1DC1432-1MC1432-1
alpha1DhumanCHO-K1C1433-1DC1433-1MC1433-1
alpha2AhumanCHO-K1C1434-1DC1434-1MC1434-1
alpha2AhumanCHO-K1C1434-1aDC1434-1aMC1434-1a
alpha2BhumanCHO-K1C1435-1DC1435-1MC1435-1
alpha2ChumanCHO-K1C1436-1DC1436-1MC1436-1
beta1humanHEK293TH1437H1437H1437
beta1humanCHO-K1C1437-1DC1437-1MC1437-1
beta2humanCHO-K1C1438-1aDC1438-1aMC1438-1a
beta3humanHEK293TC1439aDC1439aMC1439a
AnaphylatoxinC3AR1humanHEK293TC1222DC1222MC1222
C5R1humanHEK293TC1221DC1221MC1221
AngiotensinAT1humanHEK293TH1417DH1417MH1417
ApelinAPJhumanHEK293TC1196aDC1196aMC1196a
APJhumanCHO-K1C1196-1DC1196-1MC1196-1
Bile AcidGPBAhumanCHO-K1C1361-1DC1361-1MC1361-1
GPBAhumanCHO-K1C1361-1aDC1361-1aMC1361-1a
GPBAratCHO-K1Cr1361-1DCr1361-1MCr1361-1
GPBAmouseCHO-K1Cm1361-1DCm1361-1MCm1361-1
GPBA Mutant W83GhumanCHO-K1C1361-1MT1DC1361-1MT1MC1361-1MT1
GPBA Mutant W83AhumanCHO-K1C1361-1MT2DC1361-1MT2MC1361-1MT2
GPBA Mutant V88LhumanCHO-K1C1361-1MT3DC1361-1MT3MC1361-1MT3
GPBA Mutant Y89AhumanCHO-K1C1361-1MT4DC1361-1MT4MC1361-1MT4
GPBA Mutant Y89HhumanCHO-K1C1361-1MT5DC1361-1MT5MC1361-1MT5
GPBA Mutant F96AhumanCHO-K1C1361-1MT6DC1361-1MT6MC1361-1MT6
GPBA Mutant W237AhumanCHO-K1C1361-1MT7DC1361-1MT7MC1361-1MT7
GPBA Mutant W240AhumanCHO-K1C1361-1MT8DC1361-1MT8MC1361-1MT8
BombesinBB1humanHEK293TC1211DC1211MC1211
BB1ratC6C1211-1DC1211-1MC1211-1
BB2humanHEK293TC1215DC1215MC1215
BB3humanHEK293TC1214DC1214MC1214
BB3humanHEK293TH1214DH1214MH1214
BradykininB1humanHEK293TC1198aDC1198aMC1198a
B1mouseHEK293TCm1198DCm1198MCm1198
B2humanHEK293TH1199DH1199MH1199
B2mouseHEK293TCm1199DCm1199MCm1199
B2ratHEK293TCr1199DCr1199MCr1199
B2dogHEK293TCd1199DCd1199MCd1199
B2rhesus monkeyHEK293TCpr1199DCpr1199MCpr1199
B2guinea pigHEK293TCc1199DCc1199MCc1199
B2rabbitHEK293TCb1199DCb1199MCb1199
CalcitoninCALCRLhumanHEK293TC1232DC1232MC1232
CALCRLhumanCHO-K1C1232-1DC1232-1MC1232-1
CGRPhumanCHO-K1C1515-1DC1515-1MC1515-1
AM1humanCHO-K1C1516-1DC1516-1MC1516-1
AM2humanCHO-K1C1517-1DC1517-1MC1517-1
CThumanHEK293TH1231DH1231MH1231
CThumanCHO-K1C1231-1ADC1231-1AMC1231-1A
CThumanCHO-K1C1231-1BDC1231-1BMC1231-1B
AMY1humanCHO-K1C1509-1aDC1509-1aMC1509-1a
AMY2humanCHO-K1C1510-1aDC1510-1aMC1510-1a
AMY2humanCHO-K1C1510-1bDC1510-1bMC1510-1b
AMY3humanCHO-K1C1511-1aDC1511-1aMC1511-1a
Calcium-SensingCaSRhumanHEK293TC1233DC1233MC1233
CaSRratHEK293THr1233DHr1233MHr1233
CannabinoidCB1humanHEK293TC1229DC1229MC1229
CB1human CHO-K1C1229-1aDC1229-1aMC1229-1a
CB1humanCHO-K1C1229-1DC1229-1MC1229-1
CB1ahumanCHO-K1C1512-1DC1512-1MC1512-1
CB1bhumanCHO-K1C1513-1DC1513-1MC1513-1
CB1mouseCHO-K1Cm1229-1ADCm1229-1AMCm1229-1A
CB1mouseCHO-K1Cm1229-1BDCm1229-1BMCm1229-1B
CB2humanCHO-K1C1230-1DC1230-1MC1230-1
CB2humanCHO-K1C1230-1aDC1230-1aMC1230-1a
GPR55humanHEK293TH1113H1113H1113
GPR55humanHEK293TC1113bDC1113bMC1113b
ChemokineCCR1humanHEK293TC1009DC1009MC1009
CCR1humanHEK293T Gαqi5CG1009DCG1009MCG1009
CCR2humanHEK293TC1010DC1010MC1010
CCR3humanHEK293TC1011DC1011MC1011
CCR3human HEK293T Gαqi5CG1011DCG1011MCG1011
CCR4humanHEK293TC1012DC1012MC1012
CCR4humanHEK293T Gαqi5CG1012DCG1012MCG1012
CCR5humanHEK293TC1013aDC1013aMC1013a
CCR5humanHEK293TC1013bDC1013bMC1013b
CCR5humanHEK293T Gαqi5CG1013DCG1013
MCG1013
CCR6humanHEK293TC1014aDC1014aMC1014a
CCR6humanHEK293TC1014bDC1014bMC1014b
CCR6mouseHEK293TCm1014DCm1014MCm1014
CCR7humanHEK293TC1015DC1015MC1015
CCR7humanHEK293T Gαqi5CG1015DCG1015MCG1015
CCR8humanHEK293TC1016DC1016MC1016
CCR8humanHEK293TC1016aDC1016aMC1016a
CCR8humanHEK293T Gαqi5CG1016DCG1016MCG1016
CCR9dogHEK293T Gαqi5CGd1017DCGd1017MCGd1017
CCR9humanHEK293TC1017DC1017MC1017
CCR9humanHEK293TC1017aDC1017aMC1017a
CCR9humanHEK293T Gαqi5CG1017DCG1017MCG1017
CCR9humanHEK293T Gαqi5CG1017ADCG1017AMCG1017A
CCR9mouseHEK293TCm1017DCm1017MCm1017
CCR9mouseHEK293T Gαqi5CGm1017DCGm1017MCGm1017
CCR9ratHEK293T Gαqi5CGr1017DCGr1017MCGr1017
CCR10humanHEK293TC1018DC1018MC1018
CCR10humanCHO-K1 Gαqi5CG1018-1DCG1018-1MCG1018-1
CMKLR1humanHEK293TC1147DC1147MC1147
CMKLR1humanHEK293T Gαqi5CG1147DCG1147MCG1147
CX3CR1humanHEK293TC1008DC1008MC1008
CX3CR1humanHEK293T Gαqi5CG1008aDCG1008aMCG1008a
CX3CR1humanHEK293T Gαqi5CG1008bDCG1008bMCG1008b
CXCR1humanHEK293TC1001aDC1001aMC1001a
CXCR1humanHEK293T Gαqi5CG1001DCG1001MCG1001
CXCR2humanHEK293TC1002DC1002MC1002
CXCR2humanHEK293T Gαqi5CG1002DCG1002MCG1002
CXCR3humanHEK293TC1003DC1003MC1003
CXCR3humanHEK293TC1003aDC1003aMC1003a
CXCR3humanHEK293T Gαqi5CG1003DCG1003MCG1003
CXCR4humanHEK293TC1004-1DC1004-1MC1004-1
CXCR4humanHEK293T Gαqi5CG1004DCG1004MCG1004
CXCR5humanHEK293TC1005DC1005MC1005
CXCR5humanHEK293TC1005aDC1005aMC1005a
CXCR5humanCHO-K1C1005-1DC1005-1MC1005-1
CXCR5humanCHO-K1C1005-1aDC1005-1aMC1005-1a
CXCR6humanHEK293TC1006DC1006MC1006
CXCR6humanCHO-K1C1006-1DC1006-1MC1006-1
CXCR6humanHEK293T Gαqi5CG1006DCG1006MCG1006
CXCR7humanHEK293TC1150DC1150MC1150
XCR1humanHEK293TC1007DC1007MC1007
CholecystokininCCK1humanCHO-K1C1038-1aDC1038-1aMC1038-1a
CCK1humanHEK293TC1038DC1038MC1038
CCK2humanHEK293TH1039DH1039MH1039
Citric Acid Cycle
Intermediates
GPR91humanCHO-K1C1144-1DC1144-1MC1144-1
GPR99humanCHO-K1C1132-1DC1132-1MC1132-1
Corticotrophin-Releasing
Factor
CRF1humanHEK293TC1040DC1040MC1040
CRF1humanHEK293T Gαqi5CG1040DCG1040MCG1040
CRF2humanHEK293TC1041DC1041MC1041
CRF2humanHEK293TGα16CG1041DCG1041MCG1041
DopamineD1humanHEK293TC1335DC1335MC1335
D1humanHEK293TH1335DH1335MH1335
D2humanHEK293TC1336DC1336MC1336
D2humanHEK293TC1336aDC1336aMC1336a
D2 GhrelinhumanHEK293TC1514DC1514MC1514
D4humanHEK293TC1338DC1338MC1338
D4humanHEK293T Gαqi5CG1338DCG1338MCG1338
D5humanHEK293TC1339DC1339MC1339
EndothelinETAhumanCHO-K1C1216-1DC1216-1MC1216-1
ETAratCHO-K1Cr1216-1DCr1216-1MCr1216-1
ETBhumanCHO-K1C1217-1DC1217-1MC1217-1
Free Fatty AcidGPR119humanCHO-K1C1298-1aDC1298-1aMC1298-1a
GPR119humanHEK293TC1298DC1298MC1298
GPR119mouseCHO-K1Cm1298-1DCm1298-1MCm1298-1
GPR120humanHEK293TC1294DC1294MC1294
GPR120humanHEK293T Gαqi5CG1294DCG1294MCG1294
GPR120humanCHO-K1C1294-1DC1294-1MC1294-1
GPR120LhumanHEK293TC1522DC1522MC1522
GPR120LhumanHEK293T β-Arrestin2CA1522DCA1522MCA1522
GPR120mouseHEK293T Gαqi5CGm1294DCGm1294MCGm1294
GPR120ratHEK293TCr1294DCr1294MCr1294
GPR40cynomolgus monkeyCHO-K1Cpc1101-1DCpc1101-1MCpc1101-1
GPR40dogCHO-K1Cd1101-1DCd1101-1MCd1101-1
GPR40humanHEK293TC1101DC1101MC1101
GPR40humanCHO-K1C1101-1DC1101-1MC1101-1
GPR40humanCHO-K1C1101-1ADC1101-1AMC1101-1A
GPR40mouseHEK293TCm1101DCm1101MCm1101
GPR40ratHEK293TCr1101DCr1101MCr1101
GPR40ratCHO-K1Cr1101-1DCr1101-1MCr1101-1
GPR40rhesus monkeyCHO-K1Cpr1101-1DCpr1101-1MCpr1101-1
GPR41humanHEK293TC1102DC1102MC1102
GPR41humanCHO-K1 Gα16C1102-1DCG1102-1MC1102-1
GPR41humanHEK293T Gαqi5CG1102DCG1102MCG1102
GPR41mouseCHO-K1 Gα16CGm1102-1DCGm1102-1MCGm1102-1
GPR41ratHEK293TCr1102DCr1102MCr1102
GPR43humanHEK293TC1104DC1104MC1104
GPR43humanCHO-K1C1104-1DC1104-1MC1104-1
GPR43humanCHO-K1 Gα16HG1104-1DHG1104-1MHG1104-1
GPR43mouseHEK293TCm1104DCm1104MCm1104
GPR43ratHEK293TCr1104DCr1104MCr1104
GPR43dogCHO-K1Cd1104-1ADCd1104-1AMCd1104-1A
GPR43dogCHO-K1Cd1104-1BDCd1104-1BMCd1104-1B
GPR43cynomolgus monkeyCHO-K1Cpc1104-1ADCpc1104-1AMCpc1104-1A
GPR43cynomolgus monkeyCHO-K1Cpc1104-1BDCpc1104-1BMCpc1104-1B
GPR43rhesus monkeyCHO-K1Cpr1104-1ADCpr1104-1AMCpr1104-1A
GPR43rhesus monkeyCHO-K1Cpr1104-1BDCpr1104-1BMCpr1104-1B
GPR84humanCHO-K1C1137-1DC1137-1MC1137-1
GPR84humanCHO-K1 Gαqi5CG1137-1DCG1137-1MCG1137-1
Frizzled SMOhumanHEK293TC1442DC1442MC1442
SMOhumanHEK293TH1442DH1442MH1442
GalaninGAL1humanCHO-K1 Gαqi5CG1178-1DCG1178-1MCG1178-1
GAL1humanHEK293TC1178DC1178MC1178
GAL2humanCHO-K1C1179-1DC1179-1MC1179-1
GhrelinGhrelinhumanHEK293TC1197bDC1197bMC1197b
GhrelinhumanCHO-K1C1197-1DC1197-1MC1197-1
GhrelinmouseHEK293TCm1197DCm1197MCm1197
GlucagonGHRHhumanHEK293TC1291DC1291MC1291
GIPhumanHEK293TC1290DC1290MC1290
GIPhumanHEK293T β-Arrestin2CA1290DCA1290MCA1290
GIPmouseHEK293TCm1290DCm1290MCm1290
GIPratHEK293TCr1290DCr1290MCr1290
GIPdogHEK293TCd1290DCd1290MCd1290
GIPdogHEK293TCd1290aDCd1290aMCd1290a
GIPrabbitHEK293TCb1290DCb1290MCb1290
GIPrhesus monkeyHEK293TCpr1290aDCpr1290aMCpr1290a
GIPferretHEK293TCf1290DCf1290MCf1290
GIPferretHEK293TCf1290aDCf1290aMCf1290a
GLP-1humanHEK293TC1267DC1267MC1267
GLP-1humanCHO-K1C1267-1DC1267-1MC1267-1
GLP-1humanCHO-K1C1267-1aDC1267-1aMC1267-1a
GLP-1humanCHO-K1 β-Arrestin2CA1267-1DCA1267-1MCA1267-1
GLP-1cynomolgus monkeyCHO-K1Cpc1267-1DCpc1267-1MCpc1267-1
GLP-1cynomolgus monkeyCHO-K1Cpc1267-1aDCpc1267-1aMCpc1267-1a
GLP-1ratCHO-K1Cr1267-1DCr1267-1MCr1267-1
GLP-1dogCHO-K1Cd1267-1DCd1267-1MCd1267-1
GLP-1mouse CHO-K1Cm1267-1DCm1267-1MCm1267-1
GLP-1mouse CHO-K1Cm1267-1aDCm1267-1aMCm1267-1a
GLP-2humanHEK293TC1268DC1268MC1268
GLP-2ratHEK293TCr1268DCr1268MCr1268
GlucagonhumanHEK293TC1266DC1266MC1266
GlucagonhumanHEK293TC1266ADC1266AMC1266A
GlucagonhumanCHO-K1C1266-1DC1266-1MC1266-1
GlucagonhumanCHO-K1C1266-1aDC1266-1aMC1266-1a
GlucagonhumanCHO-K1 β-Arrestin2CA1266-1DCA1266-1MCA1266-1
Glucagoncynomolgus monkeyCHO-K1Cpc1266-1DCpc1266-1MCpc1266-1
Glucagoncynomolgus monkeyCHO-K1Cpc1266-1aDCpc1266-1aMCpc1266-1a
Glucagoncynomolgus monkeyHEK293TCpc1266DCpc1266MCpc1266
Glucagoncynomolgus monkeyHEK293TCpc1266aDCpc1266aMCpc1266a
SecretinhumanCHO-K1C1228-1DC1228-1MC1228-1
Glycoprotein HormoneTSHhumanHEK293TH1177DH1177MH1177
TSHratHEK293TC1177-1DC1177-1MC1177-1
Gonadotrophin-Releasing
Hormone
GnRHhumanHEK293TC1283DC1283MC1283
HistamineH1humanHEK293TC1027DC1027MC1027
H1mouseHEK293TCm1027DCm1027MCm1027
H2humanHEK293TC1028DC1028MC1028
H3humanHEK293TC1029DC1029MC1029
H3humanHEK293T Gαqi5CG1029DCG1029MCG1029
H3mouseHEK293TCm1029DCm1029MCm1029
H3 mouseCHO-K1Cm1029-1DCm1029-1MCm1029-1
H4humanHEK293TC1030DC1030MC1030
H4humanHEK293T Gαqi5CG1030DCG1030MCG1030
H4mouseHEK293TCm1030DCm1030MCm1030
H4mouseHEK293T Gαqi5CGm1030DCGm1030MCGm1030
Hydroxycarboxylic acid GPR81humanHEK293T
KiSS1-Derived PeptideKiSS1humanCHO dhfr-C1036DC1036MC1036
KiSS1ratCHO dhfr-C1036-1DC1036-1MC1036-1
Leukotriene/LipoxinALXhumanHEK293TC1244DC1244MC1244
BLT1humanHEK293TH1165aH1165aH1165a
BLT2humanHEK293TC1272DC1272MC1272
BLT2humanHEK293TC1272ADC1272AMC1272A
BLT2humanHEK293TC1272bDC1272bMC1272b
BLT2humanHEK293TC1272cDC1272cMC1272c
BLT2monkeyHEK293TCp1272aDCp1272aMCp1272a
BLT2monkeyHEK293TCp1272DCp1272MCp1272
BLT2mouseHEK293TCm1272aDCm1272aMCm1272a
BLT2mouseHEK293TCm1272DCm1272MCm1272
CysLT1humanHEK293TC1308DC1308MC1308
CysLT2humanHEK293TC1307DC1307MC1307
OXEhumanHEK293T
LysophospholipidGPR87humanRH7777C1140-6DC1140-6MC1140-6
LPA1humanRH7777C1048-6DC1048-6MC1048-6
LPA1mouseRH7777Cm1048-6ADCm1048-6AMCm1048-6A
LPA1mouseRH7777Cm1048-6BDCm1048-6BMCm1048-6B
LPA1ratRH7777Cr1048-6BDCr1048-6BMCr1048-6B
LPA2humanRH7777C1050-6DC1050-6MC1050-6
LPA2humanCHO-K1C1051-1DC1050-1MC1051-1
LPA3humanRH7777C1053-6DC1053-6MC1053-6
LPA3humanRH7777C1053-6aDC1053-6aMC1053-6a
LPA4humanCHO-K1C1087-1aDC1087-1aMC1087-1a
LPA4humanCHO-K1C1087-1bDC1087-1bMC1087-1b
LPA5humanRH7777C1145-6DC1145-6MC1145-6
LPA5mouseRH7777Cm1145-6DC1145-6MCm1145-6
S1P1humanCHO-K1C1047-1DC1047-1MC1047-1
S1P1humanCHO-K1 Gαqi5CG1047-1DCG1047-1MCG1047-1
S1P2humanCHO-K1C1051-1DC1051-1MC1051-1
S1P2humanCHO-K1 Gαqi5CG1051-1DCG1051-1MCG1051-1
S1P2mouseCHO-K1Cm1051-1DCm1051-1MCm1051-1
S1P2ratCHO-K1Cr1051-1DCr1051-1MCr1051-1
S1P3humanRH7777C1049-6DC1049-6MC1049-6
S1P3humanCHO-K1C1049-1DC1049-1MC1049-1
S1P3humanCHO-K1 Gαqi5CG1049-1DCG1049-1MCG1049-1
S1P3mouseCHO-K1 Gαqi5CGm1049-1DCGm1049-1MCGm1049-1
S1P3ratCHO-K1 Gαqi5CGr1049-1DCGr1049-1MCGr1049-1
S1P4humanCHO-K1 Gαqi5CG1052-1DCG1052-1MCG1052-1
S1P4mouseCHO-K1 Gαqi5CGm1052-1DCGm1052-1MCGm1052-1
S1P4ratCHO-K1 Gαqi5CGr1052-1DCGr1052-1MCGr1052-1
S1P5humanCHO-K1C1054-1DC1054-1MC1054-1
S1P5humanCHO-K1 Gαqi5CG1054-1DCG1054-1MCG1054-1
Melanin-Concentrating
Hormone
MCH1humanHEK293T Gαqi5C1031-3DC1031-3MC1031-3
MCH1ratHEK293T Gαqi5C1031-4DC1031-4MC1031-4
MCH2humanCHO dhfr-C1032DC1032MC1032
MelanocortinMC1humanHEK293TC1340DC1340MC1340
MC4humanHEK293TH1343H1343H1343
MelatoninMT1humanCHO-K1C1223-1DC1223-1MC1223-1
MT2humanHEK293T Gαqi5C1224DC1224MC1224
MT2mouseHEK293TCm1224DCm1224MCm1224
MT2ratHEK293TCr1224DCr1224MCr1224
Metabotropic GlutamatemGlu1humanCHO-K1C1188-1DC1188-1MC1188-1
mGlu2humanHEK293TC1189aDC1189aMC1189a
mGlu2humanHEK293T Gαqi5HG1189HG1189HG1189
mGlu2humanHEK293T Gαqi5HG1189aHG1189aHG1189a
mGlu2ratHEK293T Gαqi5HGr1189HGr1189HGr1189
mGlu3humanHEK293T Gαqi5CG1190DCG1190MCG1190
mGlu4dogHEK293T Gαqi5CGd1191DCGd1191MCGd1191
mGlu4dogCHO-K1 Gαqi5HGd1191-1DHGd1191-1MHGd1191-1
mGlu4humanHEK293TC1191aDC1191aMC1191a
mGlu4humanHEK293T Gαqi5CG1191DCG1191MCG1191
mGlu4mouseCHO-K1 Gαqi5HGm1191-1aDHGm1191-1aMHGm1191-1a
mGlu4mouseCHO-K1 Gαqi5HGm1191-1bDHGm1191-1bMHGm1191-1b
mGlu4mouseCHO-K1 Gαqi5HGm1191-1cDHGm1191-1cMHGm1191-1c
mGlu4mouseCHO-K1 Gαqi5HGm1191-1dDHGm1191-1dMHGm1191-1d
mGlu4ratHEK293TCr1191DCr1191MCr1191
mGlu5humanHEK293TC1192DC1192MC1192
mGlu6humanHEK293TC1193DC1193MC1193
mGlu6humanHEK293T Gαqi5CG1193DCG1193MCG1193
mGlu7humanHEK293TC1194DC1194MC1194
mGlu7humanHEK293T Gαqi5CG1194DCG1194MCG1194
mGlu8humanHEK293TC1195DC1195MC1195
mGlu8humanHEK293TC1195aDC1195aMC1195a
mGlu8humanHEK293T Gαqi5CG1195DCG1195MCG1195
mGlu8humanCHO-K1C1195-1aDC1195-1aMC1195-1a
MotilinmotilinhumanHEK293TH1297H1297H1297
MuscarinicM1humanCHO-K1C1022-1DC1022-1MC1022-1
M1humanCHO-K1C1022-1aDC1022-1aMC1022-1a
M2humanCHO-K1C1023-1DC1023-1MC1023-1
M3humanCHO-K1C1024-1DC1024-1MC1024-1
M3mouseCHO-K1Cm1024-1DCm1024-1MCm1024-1
M4humanCHO-K1C1025-1DC1025-1MC1025-1
M4humanCHO-K1 Gαqi5CG1025-1DCG1025-1MCG1025-1
M5humanCHO-K1C1026-1DC1026-1MC1026-1
N-formylpeptideFPR1humanHEK293T Gαqi5CG1243DCG1243MCG1243
Neuromedin UNMU1humanHEK293TC1122DC1122MC1122
NMU2humanHEK293TC1213DC1213MC1213
Neuropeptide FF/AFNPFF1humanHEK293TC1363DC1363MC1363
NPFF2humanHEK293T Gαqi5CG1364DCG1364MCG1364
Neuropeptide SNPSmouseHEK293TC1355-1DC1355-1MC1355-1
NPShumanHEK293TC1355aDC1355aMC1355a
NPS(2)humanHEK293TC1356DC1356MC1356
NPSIle107humanHEK293TC1355-2DC1355-2MC1355-2
Neuropeptide W/BNPBW1ratHEK293T Gαqi5C1124-1DC1124-1MC1124-1
NPBW1humanHEK293T Gαqi5C1124DC1124MC1124
NPBW2humanHEK293T Gαqi5C1133DC1133MC1133
Neuropeptide YY1humanCHO-K1 Gαqi5CG1273-1DCG1273-1MCG1273-1
Y2humanCHO-K1 Gαqi5CG1274-1DCG1274-1MCG1274-1
Y2ratCHO-K1Cr1274-1DCr1274-1MCr1274-1
Y4humanCHO-K1C1300-1DC1300-1MC1300-1
Y4humanCHO-K1 Gαqi5CG1300-1DCG1300-1MCG1300-1
Y5humanHEK293TC1275aDC1275aMC1275a
Y5humanHEK293T Gαqi5CG1275DCG1275MCG1275
NeurotensinNTS1humanCHO-K1C1276-1DC1276-1MC1276-1
NTS2humanCHO-K1C1277-1DC1277-1MC1277-1
NTS2humanHEK293TC1277DC1277MC1277
NTS2humanHEK293TC1277aDC1277aMC1277a
Nicotinic AcidGPR109AhumanCHO-K1C1370-1DC1370-1MC1370-1
GPR109BhumanCHO-K1C1059-1DC1059-1MC1059-1
GPR81humanHEK293TC1134DC1134MC1134
OpioiddeltahumanCHO-K1C1351-1DC1351-1MC1351-1
deltahumanCHO-K1 Gαqi5CG1351-1DCG1351-1MCG1351-1
deltahumanCHO-K1CA1351-1DCA1351-1MCA1351-1
deltaratCHO dhfr-C1351DC1351MC1351
kappahumanCHO-K1C1352-1aDC1352-1aMC1352-1a
kappahumanCHO-K1 Gαqi5CG1352-1DCG1352-1MCG1352-1
kappahumanCHO-K1CA1352-1aDCA1352-1aMCA1352-1a
kappahumanHEK293TC1352DC1352MC1352
kapparatCHO dhfr-Cr1352-8DCr1352-8MCr1352-8
muhumanCHO-K1C1350-1aDC1350-1aMC1350-1a
muhumanCHO-K1 Gαqi5CG1350-1aDCG1350-1aMCG1350-1a
muhumanCHO-K1CA1350-1aDCA1350-1aMCA1350-1a
muratCHO dhfr-Cr1350-1aDCr1350-1aMCr1350-1a
mu Mutant Y150FhumanCHO-K1C1350-1MT1DC1350-1MT1MC1350-1MT1
mu Mutant Y150AhumanCHO-K1C1350-1MT2DC1350-1MT2MC1350-1MT2
mu Mutant M153AhumanCHO-K1C1350-1MT3DC1350-1MT3MC1350-1MT3
mu Mutant H299NhumanCHO-K1C1350-1MT4DC1350-1MT4MC1350-1MT4
mu Mutant H299AhumanCHO-K1C1350-1MT5DC1350-1MT5MC1350-1MT5
NOPhumanCHO-K1C1354-1DC1354-1MC1354-1
NOPhumanCHO-K1 Gαqi5CG1354-1DCG1354-1MCG1354-1
NOPhumanCHO-K1 β-Arrestin2CA1354-1DCA1354-1MCA1354-1
NOPhumanHEK293TC1354aDC1354aMC1354a
NOPratCHO dhfr-Cr1354DCr1354MCr1354
OrexinOX1humanCHO-K1C1033-1DC1033-1MC1033-1
OX2humanCHO-K1C1034-1DC1034-1MC1034-1
OrphanGPR3humanHEK293TC1091DC1091MC1091
GPR34humanHEK293T Gαqi5CG1095DCG1095MCG1095
GPR35dogHEK293T Gα16CGd1096DCGd1096MCGd1096
GPR35dogCHO-K1 Gα16CGd1096-1DCGd1096-1MCGd1096-1
GPR35mouseCHO-K1Cm1096-1DCm1096-1MCm1096-1
GPR35mouseCHO-K1 Gα16CGm1096-1DCGm1096-1MCGm1096-1
GPR35 (short form)humanCHO-K1C1096-1DC1096-1MC1096-1
GPR35 (short form)humanCHO-K1 β-Arrestin2CA1096-1DCA1096-1MCA1096-1
GPR35 (short form)humanCHO-K1 Gα16CG1096-1DCG1096-1MCG1096-1
GPR35 (short form)humanHEK293T Gα16CG1096DCG1096MCG1096
GPR35 (long form)humanCHO-K1 β-Arrestin2CA1523-1DCA1523-1MCA1523-1
GPR35 (long form) T108M MutanthumanCHO-K1 β-Arrestin2CA1524-1DCA1524-1MCA1524-1
GPR37L1humanHEK293TC1098DC1098MC1098
GPR50humanHEK293TC1110DC1110MC1110
GPR85humanHEK293TC1138DC1138MC1138
GPR85humanCHO-K1C1138-1DC1138-1MC1138-1
GPR142humanHEK293TC1286DC1286MC1286
GPR142humanHEK293TC1286aDC1286aMC1286a
GPR151humanCHO-K1 Gα16 Gαqi5CG1181-1DCG1181-1MCG1181-1
MRGX1humanCHO dhfr-Gαqi5C1256DC1256MC1256
MRGX2humanHEK293T Gαqi5C1257DC1257MC1257
MRGX2humanHEK293TC1257aDC1257aMC1257a
MAS1humanHEK293TC1225DC1225MC1225
OxysterolEBI2humanCHO-K1 Gαqi5CG1242-1DCG1242-1MCG1242-1
EBI2mouseCHO-K1 Gαqi5CGm1242-1DCGm1242-1MCGm1242-1
EBI2mouseCHO-K1Cm1242-1DCm1242-1MCm1242-1
Parathyroid HormonePTH1humanHEK293TC1301DC1301MC1301
PTH2humanHEK293TH1302H1302H1302
Platelet-Activating FactorPAFhumanHEK293TC1218DC1218MC1218
ProkineticinPK1humanCHO-K1C1128-1DC1128-1MC1128-1
PK2humanCHO-K1C1127-1aDC1127-1aMC1127-1a
PK2 mutanthumanCHO-K1C1127CT-1DC1127DCT-1MC1127MCT-1
Prolactin-Releasing PeptidePrRPhumanCHO dhfr-C1037DC1037MC1037
ProstanoidDP1humanHEK293TC1200DC1200MC1200
DP2humanHEK293TH1105DH1105MH1105
DP2humanHEK293TH1105aDH1105aMH1105a
EP1humanHEK293TC1201aDC1201aMC1201a
EP2humanHEK293TC1202DC1202MC1202
EP2mouseHEK293TCm1202DCm1202MCm1202
EP2mouseHEK293TCm1202-3DCm1202-3MCm1202-3
EP2ratHEK293TCr1202DCr1202MCr1202
EP2ratHEK293TCr1202-134DCr1202-134MCr1202-134
EP3humanCHO-K1C1203-1DC1203-1MC1203-1
EP3humanCHO-K1C1203-1aDC1203-1aMC1203-1a
EP3humanCHO-K1C1203-1bDC1203-1bMC1203-1b
EP3humanCHO-K1C1203-1cDC1203-1DCMC1203-1MC
EP3humanCHO-K1C1203-1dDC1203-1dMC1203-1d
EP4humanHEK293TC1204DC1204MC1204
FPhumanHEK293TC1205DC1205MC1205
IP1humanCHO-K1C1206-1DC1206-1MC1206-1
TPhumanHEK293TC1365DC1365MC1365
TPhumanHEK293TH1365H1365H1365
Protease-ActivatedPAR1humanCHO-K1C1207-1DC1207-1MC1207-1
PAR1humanHeLaC1207-7DC1207-7MC1207-7
PAR2humanHeLaC1208-7DC1208-7MC1208-7
PAR4humanHeLaC1210-7DC1210-7MC1210-7
Proton-Sensing ReceptorsGPR4humanHEK293TC1100DC1100MC1100
GPR4humanHEK293TCA1100DCA1100MCA1100
GPR65humanHEK293TC1121DC1121MC1121
GPR65humanHEK293TCA1121DCA1121MCA1121
GPR65humanHEK293TC1121aDC1121aMC1121a
GPR68humanHEK293TC1123DC1123MC1123
GPR68humanHEK293TCA1123DCA1123MCA1123
GPR132humanHEK293TCA1066DCA1066MCA1066
PurinergicGPR17 (long form)human1321N1C1076-3DC1076-3MC1076-3
GPR17 (long form)human1321N1C1076-3aDC1076-3aMC1076-3a
GPR17 (short form)human1321N1C1526-3DC1526-3MC1526-3
GPR17mouse1321N1Cm1526-3DCm1526-3MCm1526-3
GPR17rat1321N1Cr1526-3DCr1526-3MCr1526-3
P2Y1human1321N1C1160-3DC1160-3MC1160-3
P2Y2human1321N1C1161-3DC1161-3MC1161-3
P2Y2humanHEK293TC1161DC1161MC1161
P2Y2rat1321N1Cr1161-3DCr1161-3MCr1161-3
P2Y4human1321N1C1162-3DC1162-3MC1162-3
P2Y6human1321N1C1164-3DC1164-3MC1164-3
P2Y11human1321N1C1169-3DC1169-3MC1169-3
P2Y12human1321N1C1170-3DC1170-3MC1170-3
P2Y12ratCHO dhfr-C1170-1DC1170-1MC1170-1
P2Y13human1321N1C1139-3DC1139-3MC1139-3
P2Y14humanHEK293TC1057DC1057MC1057
P2Y14humanHEK293T Gαqi5CG1057DCG1057MCG1057
P2Y14ratHEK293T Gαqi5CGr1057DCGr1057MCGr1057
P2Y14monkeyHEK293T Gαqi5CGp1057DCGp1057MCGp1057
RelaxinRXFP1humanHEK293TC1287DC1287MC1287
RXFP1humanHEK293TC1287NTaDC1287NTaMC1287NTa
RXFP1humanHEK293TC1287NTbDC1287NTbMC1287NTb
RXFP2humanHEK293TC1289NTaDC1289NTaMC1289NTa
RXFP2humanHEK293TC1289NTbDC1289NTbMC1289NTb
RXFP3humanHEK293TC1306DC1306MC1306
Serotonin5-HT1AhumanHEK293TC1319DC1319MC1319
5-HT1AhumanHEK293TC1319aDC1319aMC1319a
5-HT1BhumanHEK293TC1320DC1320MC1320
5-HT1BhumanHEK293TC1320aDC1320aMC1320a
5-HT1BhumanHEK293T Gαqi5CG1320DCG1320MCG1320
5-HT2AhumanCHO-K1C1324-1DC1324-1MC1324-1
5-HT2AmouseHEK293TCm1324DCm1324MCm1324
5-HT2AdogHEK293TCd1324DCd1324MCd1324
5-HT2BhumanCHO-K1C1325-1DC1325-1MC1325-1
5-HT2BhumanHEK293TC1325DC1325MC1325
5-HT2BmouseHEK293TCm1325DCm1325MCm1325
5-HT2ChumanCHO-K1C1326-1DC1326-1MC1326-1
5-HT4AhumanCHO-K1C1518-1DC1518-1MC1518-1
5-HT4AmouseCHO-K1Cm1518-1DCm1518-1MCm1518-1
5-HT4BhumanCHO-K1C1330-1DC1330-1MC1330-1
5-HT4BhumanHEK293TC1330DC1330MC1330
5-HT4DhumanCHO-K1C1520-1DC1520-1MC1520-1
5-HT6humanCHO-K1C1331-1DC1331-1MC1331-1
5-HT7humanHEK293TC1334DC1334MC1334
Somatostatinsst1humanCHO-K1C1345-1aDC1345-1aMC1345-1a
sst1humanCHO-K1 Gα16CG1345-1DCG1345-1MCG1345-1
sst2humanCHO-K1C1346-1DC1346-1MC1346-1
sst2humanCHO-K1 Gα16CG1346-1DCG1346-1MCG1346-1
sst3humanCHO-K1C1347-1DC1347-1MC1347-1
sst3humanCHO-K1 Gα16CG1347-1DCG1347-1MCG1347-1
sst4humanCHO-K1C1348-1aDC1348-1aMC1348-1a
sst4humanCHO-K1 Gα16CG1348-1DCG1348-1MCG1348-1
sst5humanCHO-K1C1349-1DC1349-1MC1349-1
sst5humanCHO-K1 Gα16CG1349-1DCG1349-1MCG1349-1
TachykininNK1humanHEK293TC1303DC1303MC1303
NK2humanHEK293TC1304DC1304MC1304
NK3humanHEK293TC1305DC1305MC1305
Thyrotropin-Releasing
Hormone
TRHhumanHEK293T
Trace AmineTA1ratHEK293TC1357DC1357MC1357
TA1humanHEK293TC1357aDC1357aMC1357a
UrotensinUTratCHO dhfr-C1035-1DC1035-1MC1035-1
UThumanHEK293TC1035-1aDC1035-1aMC1035-1a
Vasoactive Intestinal
Peptide
PAC1humanHEK293TC1415DC1415MC1415
VPAC1humanCHO-K1C1292-1DC1292-1MC1292-1
VPAC2humanHEK293TH1293DH1293MH1293
Vasopressin/OxytocinOThumanCHO-K1C1299-1DC1299-1MC1299-1
OTrabbitHEK293TCb1299DCb1299MCb1299
OTrabbitHEK293TCb1299LDCb1299LMCb1299L
V1AhumanCHO-K1C1042-1DC1042-1MC1042-1
V1ArabbitHEK293TCb1042DCb1042MCb1042
V1BhumanCHO-K1C1043-1DC1043-1MC1043-1
V1BrabbitHEK293TCb1043DCb1043MCb1043
V1BrabbitHEK293TCb1043LDCb1043LMCb1043L
V2humanCHO-K1C1044-1DC1044-1MC1044-1
V2rabbitHEK293TCb1044DCb1044MCb1044
V2rabbitHEK293TCb1044LDCb1044LMCb1044L
V2dogCHO-K1Cd1044-1DCd1044-1MCd1044-1
ZincGPR39humanHEK293TH1099DH1099MH1099

Endogenous Targets

Target FamilyTargetSpeciesCells
KinaseAMPKhumanC2C12
DNA-PKhumanHela
Aryl Hydrocarbon Receptor (Nuclear Hormone Receptor)AHRhumanHep G2
AHRmouseHepa1-6
AHRhumanHG2L6.1c1 CALUX
AHRmouseH1L6.c3 CALUX
ChemokineCCR4humanH9
CCR6humanH9
CalcitoninCGRPhumanSK-N-MC
Free Fatty AcidGPR40mouseMIN6
LysophospholipidLPAhumanHuman Fibroblast-Like Synoviocytes-Rheumatoid
Melanin-Concentrating HormoneMCH1humanYS35
OpioidmuhumanSK-N-SH
Serotonin5-HThumanHuman Heart Valvular Interstitial Cells

Other Targets

Receptor FamilyReceptorSpeciesParentalStable Cell LineDivision-Arrested Cells Membranes
Integrina V b 1humanCHOB2C3001DC3001MC3001
Potassium ChannelTMEM175humanHEK293TC1527DC1527MC1527
Receptor Tyrosine KinasesTrKAhumanCHO-K1CK1001-1DCK1001-1MCK1001-1
TrKAhumanCHO-K1CK1001-1bDCK1001-1bMCK1001-1b
TrKAratCHO-K1CKr1001-1DCKr1001-1MCKr1001-1
FGFR3humanCHO-K1CK1002-1DCK1002-1MCK1002-1
FGFR3humanCHO-K1CK1002-1aDCK1002-1aMCK1002-1a
Zinc TransporterZnT3humanHelaC2001-7DC2001-7MC2001-7
ZnT8humanCHO-K1C2002-1DC2002-1MC2002-1

Parental Lines

ParentalStable Cell LinesDivision-Arrested CellsMembranes
HEK293TDC0001MC0001
HEK293T Gαqi5CG0001DCG0001MCG0001
CHO-K1DC0001-1MC0001-1
CHO-K1 Gαqi5CG0001-1DCG0001-1MCG0001-1
CHO-K1 Gα16CG0002-1DCG0002-1MCG0002-1
CHO-K1 Gα16 Gαqi5CG0003-1DCG0003-1MCG0003-1
CHO dhfr-DCD0001-1MCD0001-1
CHO-K1 NFATCK0001-1DCK0001-1MCK0001-1
1321N1DC0001-3MC0001-3
RH7777DC0001-6MC0001-6
HelaDC0001-7MC0001-7

Assay Kits

Assay KitUnit Size
(384-well)
CatalogDescriptionData
MultiScreen™ Calcium 1.0 No Wash Assay Kit1000MSCA01-1Multiscreen™ Calcium 1.0 No Wash Assay Kits provide homogeneous fluorescence-based assays for intracellular calcium mobilization detection in 96-well, 384-well and higher multiplexity. Pre-loaded with Calcium 1.0 is taken up by the cells where the lipophilic blocking groups of Calcium 1.0 are cleaved by esterases, resulting in a negatively charged fluorescent dye that stays inside cells. The fluorescence signal is greatly enhanced after binding to intracellular calcium released by cell-stimulation. Long wavelength, high sensitivity, and >100 times fluorescence enhancement make Calcium 1.0 an ideal indicator for intracellular calcium release assays measuring GPCRs, calcium channels and receptor tyrosine kinase signaling.

Multiscreen™ Calcium 1.0 No Wash Assay Kits are validated by Multiscreen™ stable cell lines.


Calcium Dose Response in MultiScreen™ A2B-HEK293T stable cell line (C1429) measured with MultiScreen™ Calcium 1.0 No Wash Assay Kit. Cells were seeded in assay buffer in a 384-well black wall clear bottom PDL-coated plate, incubated with the MultiScreen™ Calcium 1.0 No Wash Assay Kit before being treated with control agonist NECA and measured by FLIPR.
10000MSCA01-10
100000MSCA01-100
MultiScreen™ TR-FRET cAMP 1.0 No Wash Assay Kit500MSCM01-1Multiscreen™ TR-FRET cAMP 1.0 No Wash Assay Kits provide a homogenous TR-FRET assay method for adenylyl cyclase activity detection in 96-well, 384-well and higher multiplexity. α-cAMP antibody (Ab) is labeled with MultiScreen™Eu while cAMP is labeled with MultiScreen™650. In the absence of cAMP, MultiScreen™650-cAMP is bound to MultiScreen™Eu-α-cAMP-Ab to give a strong TR-FRET Emission at 655 nm. Free cAMP in the test sample competes for binding to the MultiScreen™ Eu-α-cAMP-Ab, reducing TR-FRET signal from MultiScreen™650-cAMP binding. The MultiScreen™650-cAMP only has fluorescence lifetime of nanosecond while MultiScreen™Eu-α-cAMP-Ab has much longer fluorescence lifetime value due to TR-FRET. The magnitude of TR-FRET is proportional to the concentration of cAMP in a sample.

Multiscreen™ TR-FRET cAMP 1.0 No Wash Assay Kits are validated by Multiscreen™ stable cell lines.


cAMP Dose-Response in MultiScreen™ β1-HEK293T stable cell line (C1437-1) measured with MultiScreen™ TR-FRET cAMP 1.0 No Wash Assay Kit. Cells were seeded in a 384-well solid white plate, incubated with Isoproterenol and 1mM IBMX before being treated with MultiScreen™Eu-α-cAMP-Ab and MultiScreen™650-cAMP, and measured by FlexStation 3.
5000MSCM01-10
25000MSCM01-100