MULTISCREEN™ STABLE CELL LINES

HEK293T GαQI5

Product Information

Catalog Number:
CG0001

Lot Number:
CG0001-031915

Quantity:
1 vial (2 x 106) frozen cells

Freeze Medium:
Sigma Freezing Medium (C-6164)

Host cell:
HEK293T Gαqi5

Recommended Storage:
Liquid nitrogen upon receiving

Propagation Medium: DMEM, 10% FBS

Stability:
Stable for a minimum of 2 months in continuous culture

Data Sheet

Background: Transmembrane Protein 175 (TMEM175) is an organelle specific potassium channel specifically responsible for potassium conductance in endosomes and lysosomes. TMEM175 is reported to regulate lumenal pH stability and is required for autophagosome-lysosome fusion. TMEM175 comprises a K+ channel that underlies the molecular mechanism of lysosomal K+ permeability Application: Functional assays

Figure 1. Dose-dependent stimulation of calcium flux upon treatment with ligand, measured with MultiscreenTM Calcium 1.0 No Wash Assay Kit (Multispan MSCA01).

FOR RESEARCH USE ONLY.
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