MULTISCREEN™ GPCR membranes are offered at 1 mg, 5 mg, 10 mg, 100 mg, 500 mg, and 1000 mg quantities. 1 mg to 10 mg is typically purchased for initial assay development, followed by higher quantity orders custom-prepared for HTS or repeat orders to support hit-to-lead and lead optimization. With MULTISCREEN™ GPCR stable cell lines ready to go, our maximum turnaround time is generally 1 month, with smaller quantities of membranes delivered even faster. Customers of MULTISCREEN™ GPCR membranes never have to worry about any extended delays, as they would often experience elsewhere.
Multispan’s GPCR membranes are prepared directly from our catalog of over 500 functionally well-validated MULTISCREEN™ GPCR stable cell lines. These membranes can be used in primary screens for the human GPCR target, or counterscreens against closely related GPCRs and ortholog GPCRs from rhesus monkey, cynomolgus monkey, dog, ferret, rabbit, rat, and mouse etc. The ortholog targets in MULTISCREEN™ GPCR stable cell lines are generally expression and pharmacology-matched to their human counterparts.