General Family Information
Relaxin receptors are a family of G protein-coupled receptors (GPCRs) comprised of four receptor subtypes: RXFP1, RXFP2, RXFP3, and RXFP4. Through the mediation of relaxin activity, relaxin receptors are involved in a variety of biological processes such as reproduction, anxiety, arousal, and stress response. Relaxin has potential therapeutic application in the treatment of acute heart failure, and is currently undergoing clinical studies. Research is also being done on the application of relaxin in treating asthma, cardiovascular disease, and renal disease.
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