General Family Information

Neurotensin receptors are a family of G protein-coupled receptors (GPCRs) comprised of two receptor subtypes: NTS1 and NTS2. These receptors bind neurotensin and are primarily found within the brain and intestine. They are involved in a variety of biological processes, such as dopamine transmission, hypotension, lowering gastric acid, lipid digestion, and as an anti-apoptotic for pancreatic cells. NTS1 is currently being researched as a potential drug target for psychotic disorders.

Receptor FamilyReceptorSpeciesParentalStable Cell Lines Division-Arrested Cells Membranes
NeurotensinNTS1humanCHO-K1C1276-1DC1276-1MC1276-1
NTS2humanCHO-K1C1277-1DC1277-1MC1277-1
NTS2humanHEK293TC1277DC1277MC1277
NTS2humanHEK293TC1277aDC1277aMC1277a