General Family Information

Dopamine receptors are a family of G protein-coupled receptors (GPCRs) which are responsible for a large number of central nervous system functions, such as attention, cognitive functions, cardiovascular functions, motivation and positive reinforcement and motor activity. There are five different subtypes of dopamine receptors: D1, D2, D3, D4, and D5. Defects in any one of these transmitters has a potentially large effect on the central nervous system in the form of neurological and psychiatric disorders. These disorders include Tourette’s syndrome, Parkinson’s disease, schizophrenia, ADHD, substance abuse, and social phobias.

Receptor FamilyReceptorSpeciesParentalStable Cell Lines Division-Arrested Cells Membranes
DopamineD1humanHEK293TC1335DC1335MC1335
D1humanHEK293TH1335DH1335MH1335
D2humanHEK293TC1336DC1336MC1336
D2humanHEK293TC1336aDC1336aMC1336a
D2 GhrelinhumanHEK293TC1514DC1514MC1514
D4humanHEK293TC1338DC1338MC1338
D4humanHEK293T Gαqi5CG1338DCG1338MCG1338
D5humanHEK293TC1339DC1339MC1339