General Family Information

Galanin receptors are a family of G protein-coupled receptors (GPCRs) comprised of three different receptor subtypes: GAL1, GAL2, and GAL3. Galanin receptors are found all throughout the endocrine, peripheral, and central nervous systems, regulating a variety of biological functions such as arousal, sleep, cognition, reproduction, and metabolic and osmotic homeostasis. Galanin receptor agonists have applications in anti-seizure treatments, while antagonists have potential applications in treatments for anxiety and depression.

Receptor FamilyReceptorSpeciesParentalStable Cell Lines Division-Arrested Cells Membranes
GalaninGAL1humanCHO-K1 Gαqi5CG1178-1DCG1178-1MCG1178-1
GAL1humanHEK293TC1178DC1178MC1178
GAL2humanCHO-K1C1179-1DC1179-1MC1179-1