KiSS1-Derived Peptide Receptors
General Family Information
The KiSS1-derived peptide receptor is a G protein-coupled receptor (GPCR) involved in the regulation of puberty, fertility, and endocrine function. Agonist activity of the KiSS1 receptor results in the release of gonadotropin-releasing hormones. While full agonists have been identified for the KiSS1 receptor, no antagonists have currently been discovered.
| Receptor Family | Receptor | Species | Parental | Stable Cell Lines | Division-Arrested Cells | Membranes |
|---|---|---|---|---|---|---|
| KiSS1-Derived Peptide | KiSS1 | human | CHO dhfr- | C1036 | DC1036 | MC1036 |
| KiSS1 | rat | CHO dhfr- | C1036-1 | DC1036-1 | MC1036-1 |