General Family Information

The platelet-activating factor receptor (PAFR) is a G protein-coupled receptor (GPCR) expressed in a variety of cells within the vascular and immune system. PAFR has been found to play a role in many biological processes such as human reproduction and gas exchange, as well as skin inflammation, carcinogenesis, tumor development, and metastasis. PAFR antagonists have shown potential in the treatment of various tumors as well as skin inflammation.

Receptor FamilyReceptorSpeciesParentalStable Cell Lines Division-Arrested Cells Membranes
Platelet-Activating FactorPAFhumanHEK293TC1218DC1218MC1218