General Family Information

Anaphylatoxin receptors are a family of G protein-coupled receptors (GPCRs) that consists of C3a, C5a, and C5L2 receptors. Anaphylatoxins, also known as complement peptides, serve a major role in inflammation, and are targets for anti-inflammatory treatments. There are currently no satisfactory antagonists for the three mammalian complement peptides.

Receptor FamilyReceptorSpeciesParentalStable Cell Lines Division-Arrested Cells Membranes
AnaphylatoxinC3AR1humanHEK293TC1222DC1222MC1222
C5R1humanHEK293TC1221DC1221MC1221