General Family Information

Ghrelin receptors, also known as growth hormone secretagogue receptors, are a family of G protein-coupled receptors (GPCRs) mainly responsible for regulating body weight and energy homeostasis. Ghrelin receptor agonists have therapeutic applications in muscle degeneration and degenerative diseases, due to their HGH releasing and appetite-stimulating effects. Ghrelin receptor antagonists have therapeutic applications in obesity, due to their anorectic effect.

Receptor FamilyReceptorSpeciesParentalStable Cell Lines Division-Arrested Cells Membranes
GhrelinGhrelinhumanHEK293TC1197bDC1197bMC1197b
GhrelinhumanCHO-K1C1197-1DC1197-1MC1197-1
GhrelinmouseHEK293TCm1197DCm1197MCm1197