Serotonin GPCR Family Subtypes and Products

Serotonin (5-HT) receptors are a family of G protein-coupled receptors (GPCRs) comprised of seven subclasses of receptors: 5-HT1, with five subtypes, 5-HT2, with three subtypes,  5-HT3, 5-HT4, 5-HT5, with two subtypes, 5-HT6, and 5-HT7. Serotonin receptors play a large role in a variety of neurological processes, such as mood, appetite, learning, nausea, sleep, and memory, and are a major target for pharmaceutical and recreational drugs. 5-HT receptor agonists currently have pharmacological utility in treating anxiety, migraines, and constipation, while 5-HT receptor antagonists are used in the treatment of nausea, IBS, and psychotic disorders.