The Multispan Portfolio
Multispan’s commitment to quality and scientific excellence extends to every product in its portfolio of ready-to-use tools. These products produce data with the consistency, reliability, and physiological relevance required to bring better medicines to the clinic.
The Multispan Portfolio
Multispan’s commitment to quality and scientific excellence extends to every product in its portfolio of ready-to-use tools. These products produce data with the consistency, reliability, and physiological relevance required to bring better medicines to the clinic.
Over 1600 products for rapid, cost-effective screening and profiling.
MULTISCREEN™ Stable Cell Lines
Reliable, HTS-ready, biologically and pharmacologically relevant for cell-based GPCR screening.
Product Highlights:
- Portfolio of >1000 clonally-derived stable cell lines
- Minimally modified GPCRs and other targets directly selected in functional assays
- Validated using MULTISCREEN™ assay kits in 384-well format
- Rigorous quality control ensures that 99% of the stable cell lines pass 2-month stability
- Parental and ortholog cell lines available
Division-arrested Cells
Fast 1-day plate-to-screen workflows with excellent batch-to-batch GPCR assay consistency.
Product Highlights:
- Derived from Multispan’s, well-characterized stable cell lines
- Quality control performed in each lot for high performance functionality
- Convenient tools for cell-based high-throughput screening
- Plate and read with ready-to-go assay conditions
- Low-cost evaluation of a stable cell line or for limited number of compounds
Membrane Preparations
Highly specific and reproducible membranes for HTS GPCR ligand binding assays.
Product Highlights:
- Ideal for receptor binding assays
- High receptor density
- Prepared from Multispan’s stable cell lines for minimal lot-to-lot variability
- Two-week turnaround for rapid delivery
- Quality control by FACS for receptor surface expression
Assay Kits
Validated, high-thoroughput, no-wash, homogenous detection assays.
Product Highlights:
- No-wash, homogenous assays for calcium, cAMP, and Beta-Arrestin detection
- Validated using Multispan’s stable cell lines and division-arrested cells
- Compatible with 96-, 384-, and 1536-well formats
- Complete technical support and protocols from cells to assay
- Routinely used in our lab in compound screening campaigns
β-Arrestin Solutions
High throughput detection of biased cell signaling of unmodified GPCRs.
Product Highlights:
- First HTS β-Arrestin sensor for native GPCRs in recombinant or primary cells
- No GPCR tagging required
- Lentiviral particles carrying MULTISCREEN™ β-Arrestin sensor genes
- Parental cells stably expressing MULTISCREEN™ β-Arrestin sensors
- Custom stable cell line generation co-expression β-Arrestin sensor and GPCR
- In-licensing for institute-wide access
Custom Cell Lines
Not seeing the cell line you need in our catalog? Let Multispan put its expertise to work to generate a custom stable cell line that meets your needs.
Product Highlights:
- Coupled to functional assay development to meet HTS needs for GPCRs, kinases, NHRs, transporters, integrins, ion-channels and more
- Comparable pharmacology and expression for human and ortholog targets
- Single clones selected in relevant functional readout with customer input upfront
- Rigorous QC: RT-PCR full-length sequencing, mycoplasma, growth curve and stability testing
MULTISCREEN™ Stable Cell Lines
Reliable, HTS-ready, biologically and pharmacologically relevant for cell-based GPCR screening.
Product Highlights:
- Portfolio of >1000 clonally-derived stable cell lines
- Minimally modified GPCRs and other targets directly selected in functional assays
- Validated using MULTISCREEN™ assay kits in 384-well format
- Rigorous quality control ensures that 99% of the stable cell lines pass 2-month stability
- Parental and ortholog cell lines available
Division-arrested Cells
Fast 1-day plate-to-screen workflows with excellent batch-to-batch GPCR assay consistency.
Product Highlights:
- Derived from Multispan’s, well-characterized stable cell lines
- Quality control performed in each lot for high performance functionality
- Convenient tools for cell-based high-throughput screening
- Plate and read with ready-to-go assay conditions
- Low-cost evaluation of a stable cell line or for limited number of compounds
Membrane Preparations
Highly specific and reproducible membranes for HTS GPCR ligand binding assays.
Product Highlights:
- Ideal for receptor binding assays
- High receptor density
- Prepared from Multispan’s stable cell lines for minimal lot-to-lot variability
- Two-week turnaround for rapid delivery
- Quality control by FACS for receptor surface expression
Assay Kits
Validated, high-thoroughput, no-wash, homogenous detection assays.
Product Highlights:
- No-wash, homogenous assays for calcium, cAMP, and Beta-Arrestin detection
- Validated using Multispan’s stable cell lines and division-arrested cells
- Compatible with 96-, 384-, and 1536-well formats
- Complete technical support and protocols from cells to assay
- Routinely used in our lab in compound screening campaigns
β-Arrestin Solutions
High throughput detection of biased cell signaling of unmodified GPCRs.
Product Highlights:
- First HTS β-Arrestin sensor for native GPCRs in recombinant or primary cells
- No GPCR tagging required
- Lentiviral particles carrying MULTISCREEN™ β-Arrestin sensor genes
- Parental cells stably expressing MULTISCREEN™ β-Arrestin sensors
- Custom stable cell line generation co-expression β-Arrestin sensor and GPCR
- In-licensing for institute-wide access
Custom Cell Lines
Not seeing the cell line you need in our catalog? Let Multispan put its expertise to work to generate a custom stable cell line that meets your needs.
Product Highlights:
- Coupled to functional assay development to meet HTS needs for GPCRs, kinases, NHRs, transporters, integrins, ion-channels and more
- Comparable pharmacology and expression for human and ortholog targets
- Single clones selected in relevant functional readout with customer input upfront
- Rigorous QC: RT-PCR full-length sequencing, mycoplasma, growth curve and stability testing
Explore products by GPCR family