Free Fatty Acid GPCR Family Subtypes and Products
General Family Information
Free fatty acid receptors are a family of G protein-coupled receptors (GPCRs) comprised of four different receptor types: FFA1, FFA2, FFA3, and FFA4. While FFA1 and FFA4 receptors are activated by long-chain fatty acids, FFA2 and FFA3 receptors are activated by short-chain fatty acids. Fatty acids play a key role in metabolism and the immune response, and are currently a large research focus for therapeutic and medical applications.
| Receptor Family | Receptor | Species | Parental | Stable Cell Lines | Division-Arrested Cells | Membranes |
|---|---|---|---|---|---|---|
| Free Fatty Acid | GPR119 | human | CHO-K1 | C1298-1a | DC1298-1a | MC1298-1a |
| GPR119 | human | HEK293T | C1298 | DC1298 | MC1298 | |
| GPR119 | mouse | CHO-K1 | Cm1298-1 | DCm1298-1 | MCm1298-1 | |
| GPR120 | human | HEK293T | C1294 | DC1294 | MC1294 | |
| GPR120 | human | HEK293T Gαqi5 | CG1294 | DCG1294 | MCG1294 | |
| GPR120 | human | CHO-K1 | C1294-1 | DC1294-1 | MC1294-1 | |
| GPR120L | human | HEK293T | C1522 | DC1522 | MC1522 | |
| GPR120L | human | HEK293T β-Arrestin2 | CA1522 | DCA1522 | MCA1522 | |
| GPR120 | mouse | HEK293T Gαqi5 | CGm1294 | DCGm1294 | MCGm1294 | |
| GPR120 | rat | HEK293T | Cr1294 | DCr1294 | MCr1294 | |
| GPR40 | cynomolgus monkey | CHO-K1 | Cpc1101-1 | DCpc1101-1 | MCpc1101-1 | |
| GPR40 | cynomolgus monkey | CHO-K1 | CApr1101-1 | DCApr1101-1 | MCApr1101-1 | |
| GPR40 | cynomolgus monkey | CHO-K1 β-Arrestin2 | CApc1101-1 | DCApc1101-1 | MCApc1101-1 | |
| GPR40 | dog | CHO-K1 | Cd1101-1 | DCd1101-1 | MCd1101-1 | |
| GPR40 | human | HEK293T | C1101 | DC1101 | MC1101 | |
| GPR40 | human | CHO-K1 | C1101-1 | DC1101-1 | MC1101-1 | |
| GPR40 | human | CHO-K1 | C1101-1A | DC1101-1A | MC1101-1A | |
| GPR40 | human | CHO-K1 β-Arrestin2 | CA1101-1 | DCA1101-1 | MCA1101-1 | |
| GPR40 | mouse | HEK293T | Cm1101 | DCm1101 | MCm1101 | |
| GPR40 | rat | HEK293T | Cr1101 | DCr1101 | MCr1101 | |
| GPR40 | rat | CHO-K1 | Cr1101-1 | DCr1101-1 | MCr1101-1 | |
| GPR40 | rhesus monkey | CHO-K1 | Cpr1101-1 | DCpr1101-1 | MCpr1101-1 | |
| GPR40 | rat | CHO-K1 β-Arrestin2 | CAr1101-1 | DCAr1101-1 | MCAr1101-1 | |
| GPR41 | human | HEK293T | C1102 | DC1102 | MC1102 | |
| GPR41 | human | CHO-K1 Gα16 | C1102-1 | DCG1102-1 | MC1102-1 | |
| GPR41 | human | HEK293T Gαqi5 | CG1102 | DCG1102 | MCG1102 | |
| GPR41 | mouse | CHO-K1 Gα16 | CGm1102-1 | DCGm1102-1 | MCGm1102-1 | |
| GPR41 | rat | HEK293T | Cr1102 | DCr1102 | MCr1102 | |
| GPR43 | human | HEK293T | C1104 | DC1104 | MC1104 | |
| GPR43 | human | CHO-K1 | C1104-1 | DC1104-1 | MC1104-1 | |
| GPR43 | human | CHO-K1 Gα16 | HG1104-1 | DHG1104-1 | MHG1104-1 | |
| GPR43 | mouse | HEK293T | Cm1104 | DCm1104 | MCm1104 | |
| GPR43 | rat | HEK293T | Cr1104 | DCr1104 | MCr1104 | |
| GPR43 | dog | CHO-K1 | Cd1104-1A | DCd1104-1A | MCd1104-1A | |
| GPR43 | dog | CHO-K1 | Cd1104-1B | DCd1104-1B | MCd1104-1B | |
| GPR43 | cynomolgus monkey | CHO-K1 | Cpc1104-1A | DCpc1104-1A | MCpc1104-1A | |
| GPR43 | cynomolgus monkey | CHO-K1 | Cpc1104-1B | DCpc1104-1B | MCpc1104-1B | |
| GPR43 | rhesus monkey | CHO-K1 | Cpr1104-1A | DCpr1104-1A | MCpr1104-1A | |
| GPR43 | rhesus monkey | CHO-K1 | Cpr1104-1B | DCpr1104-1B | MCpr1104-1B | |
| GPR84 | human | CHO-K1 | C1137-1 | DC1137-1 | MC1137-1 | |
| GPR84 | human | CHO-K1 Gαqi5 | CG1137-1 | DCG1137-1 | MCG1137-1 |