Drug Safety Screening & GPCR Profiling Services
Profiling new chemotypes and lead compounds against established lists of GPCR targets is necessary to identify potential liabilities and therapeutic efficacy. Robust compound profiling early and routinely can significantly reduce both the time and cost of drug development, and increase the likelihood of success in clinical trials and market approval.
Scientific Insights
Drug Safety Screening & GPCR Profiling Services
Profiling new chemotypes and lead compounds against established lists of GPCR targets is necessary to identify potential liabilities and therapeutic efficacy. Robust compound profiling early and routinely can significantly reduce both the time and cost of drug development, and increase the likelihood of success in clinical trials and market approval.
Drug Safety Screening & GPCR Profiling Services
Profiling new chemotypes and lead compounds against established lists of GPCR targets is necessary to identify potential liabilities and therapeutic efficacy. Robust compound profiling early and routinely can significantly reduce both the time and cost of drug development, and increase the likelihood of success in clinical trials and market approval.
Discover the Multispan Advantage
Enhanced Biological Relevance
Elimination of False Positives
Detection of Allosteric Modulators
Choose the perfect cell-based GPCR profiling panel for your drug development needs
Essential Safety
MULTISCREEN™ 32-GPCR Safety Functional Cell Assay Panel
Our most cost-effective solution, focusing on critical safety and liability targets, designed for early-stage compounds or projects with limited budgets.
Recommended For:
- Basic safety screening for key liability targets
- Identifying major undesirable off-target effects
- Budget efficiency
- Screening of large compound libraries
- Chemotype or scaffold prioritization
- Assessment of both agonists and antagonists is important
Advanced Safety
MULTISCREEN™ 50-GPCR+ Safety/Liability Functional Cell Assay Panel
The 50-GPCR+ panel builds upon the core 32-GPCR panel, offering expanded coverage for critical undesirable safety targets across major receptor families, and providing a more thorough assessment of each physiological system.
Recommended For:
- Projects requiring comprehensive safety profiling
- Assessment of both agonists and antagonists is important
- Routine screening during the lead optimization phase
- Final candidate selection and risk mitigation planning
Complete Profiling
MULTISCREEN™ 235-GPCR Cell-Based Cell Assay Panel
Our complete GPCR profiling solution, providing the maximum target coverage for full pharmacological assessment. Covering 66 receptor subfamilies, this is one of the most complete GPCR screening tools available in the industry.
Recommended For:
- Research spanning multiple receptor families
- Investigating complex mechanisms of a molecule
- Drug repurposing opportunities
- New target identification
Why Our Profiling Panels Stand Out
Our Other GPCR Cell-Based Assay Profiling Panels:
MULTISCREEN™ Orphan GPCR panel: to deconvolute unknown biology
MULTISCREEN™ Ortholog GPCR Panel: to prepare for animal models
MULTISCREEN™ GPCR-subfamily: to identify target specificity among closely related targets in one of the 66 panels, such as the glucagon receptor family and the dopamine receptor family.