Dopamine Receptor Family Products GPCR Family Subtypes and Products
General Family Information
Dopamine receptors are a family of G protein-coupled receptors (GPCRs) which are responsible for a large number of central nervous system functions, such as attention, cognitive functions, cardiovascular functions, motivation and positive reinforcement and motor activity. There are five different subtypes of dopamine receptors: D1, D2, D3, D4, and D5. Defects in any one of these transmitters has a potentially large effect on the central nervous system in the form of neurological and psychiatric disorders. These disorders include Tourette’s syndrome, Parkinson’s disease, schizophrenia, ADHD, substance abuse, and social phobias.
Receptor Family | Receptor | Species | Parental | Stable Cell Lines | Division-Arrested Cells | Membranes |
---|---|---|---|---|---|---|
Dopamine | D1 | human | HEK293T | C1335 | DC1335 | MC1335 |
D1 | human | HEK293T | H1335 | DH1335 | MH1335 | |
D2 | human | HEK293T | C1336 | DC1336 | MC1336 | |
D2 | human | HEK293T | C1336a | DC1336a | MC1336a | |
D2 Ghrelin | human | HEK293T | C1514 | DC1514 | MC1514 | |
D3 | human | HEK293T Gqi5 | CG1337 | DCG1337 | MCG1337 | |
D4 | human | HEK293T | C1338 | DC1338 | MC1338 | |
D4 | human | HEK293T Gαqi5 | CG1338 | DCG1338 | MCG1338 | |
D5 | human | HEK293T | C1339 | DC1339 | MC1339 |