Neurotensin Receptor Family Products GPCR Family Subtypes and Products
General Family Information
Neurotensin receptors are a family of G protein-coupled receptors (GPCRs) comprised of two receptor subtypes: NTS1 and NTS2. These receptors bind neurotensin and are primarily found within the brain and intestine. They are involved in a variety of biological processes, such as dopamine transmission, hypotension, lowering gastric acid, lipid digestion, and as an anti-apoptotic for pancreatic cells. NTS1 is currently being researched as a potential drug target for psychotic disorders.