Histamine Receptor Family Products GPCR Family Subtypes and Products
General Family Information
Histamine receptors are a family of G protein-coupled receptors (GPCRs) comprised of 4 receptors: H1, H2, H3, and H4. Histamine receptors play a large role in the inflammatory process, itching, allergy-related asthma, muscle constriction, and gastric acid secretion. Antihistamines (specific to only H1 receptors) and other histamine receptor antagonists are commonly used as allergy medications and antacids.
Receptor Family | Receptor | Species | Parental | Stable Cell Lines | Division-Arrested Cells | Membranes |
---|---|---|---|---|---|---|
Histamine | H1 | human | HEK293T | C1027 | DC1027 | MC1027 |
H1 | mouse | HEK293T | Cm1027 | DCm1027 | MCm1027 | |
H2 | human | HEK293T | C1028 | DC1028 | MC1028 | |
H3 | human | HEK293T | C1029 | DC1029 | MC1029 | |
H3 | human | HEK293T Gαqi5 | CG1029 | DCG1029 | MCG1029 | |
H3 | mouse | HEK293T | Cm1029 | DCm1029 | MCm1029 | |
H3 | mouse | CHO-K1 | Cm1029-1 | DCm1029-1 | MCm1029-1 | |
H4 | human | HEK293T | C1030 | DC1030 | MC1030 | |
H4 | human | HEK293T Gαqi5 | CG1030 | DCG1030 | MCG1030 | |
H4 | human | HEK293T β-Arrestin2 | CA1030BA2 | DCA1030BA2 | MCA1030BA2 | |
H4 | mouse | HEK293T | Cm1030 | DCm1030 | MCm1030 | |
H4 | mouse | HEK293T Gαqi5 | CGm1030 | DCGm1030 | MCGm1030 |