Vasopressin/Oxytocin GPCR Family Subtypes and Products

Vasopressin and oxytocin receptors are a family of G protein-coupled receptors (GPCRs) found all throughout the brain and peripheral tissue, contributing to a wide range of biological functions. This family is comprised of four receptor subtypes: OT, V1A, V1B, and V2. Peripheral roles for these receptors are more established, such as uterine muscle contraction and the prevention of bodily fluid loss. V2 agonists are used to treat bleeding disorder. In addition, they also play a large role in a variety of social and psychological behaviors, such as attachment, generosity, bonding, and maternal behavior.