Prokineticin GPCR Family Subtypes and Products
General Family Information
Prokineticin receptors are a family of G protein-coupled receptors (GPCRs) comprised of two receptor subtypes: PKR1 and PKR2. Prokineticin receptors play a role in the regulation of a variety of biological processes such as circadian rhythms, GI motility, angiogenesis, hematopoiesis, and neurogenesis. Research, however, is still being done on the biology of this newly discovered family of receptors.
| Receptor Family | Receptor | Species | Parental | Stable Cell Lines | Division-Arrested Cells | Membranes |
|---|---|---|---|---|---|---|
| Prokineticin | PK1 | human | CHO-K1 | C1128-1 | DC1128-1 | MC1128-1 |
| PK2 | human | CHO-K1 | C1127-1a | DC1127-1a | MC1127-1a | |
| PK2 mutant | human | CHO-K1 | C1127CT-1 | DC1127DCT-1 | MC1127MCT-1 |