Peer-Reviewed Papers

Loss of Free Fatty Acid Receptor 2 leads to impaired islet mass and beta cell survival

GPCR Target: FFA2

Authors: Stephanie R. Villa, et al.

Company: Northwestern University Feinberg School of Medicine / Vanderbilt University / Indiana University School of Medicine / Multispan Inc. / Midwestern University

Journal: Nature, Scientific Reports volume 6, Article number: 28159 (2016)

Year Published: 2016

Homology modeling of FFA2 identifies novel agonists that potentiate insulin secretion.

GPCR Target: Free Fatty Acid

Authors: Villa SR, et al.

Company: Northwestern University / University of Illinois at Chicago / Midwestern University / Multispan / Jesse Brown Veterans Affairs Medical Center

Journal: J Investig Med. December 2017; 65(8):1116-1124

Year Published: 2017

Effects of LTB4 receptor antagonism on pulmonary inflammation in rodents and non-human primates.

GPCR Target: BLT1/BLT2

Authors: Hicks A, et al.

Company: Roche

Journal: Prostaglandins Other Lipid Mediat. June 2010; 92(1-4):33-43

Year Published: 2010

Development of a FLIPR assay for the simultaneous identification of MrgD agonists and antagonists from a single screen.

GPCR Target: MrgX1

Authors: Ajit SK, et al.

Company: Drexel University College of Medicine / Pfizer Global Research and Development

Journal: J Biomed Biotechnol. 2010; pii: 326020

Year Published: 2010

Critical Cysteine Residues in Both the Calcium-Sensing Receptor and the Allosteric Activator AMG 416 Underlie the Mechanism of Action.

GPCR Target: CaSR

Authors: Alexander ST, et al.

Company: Amgen

Journal: Mol Pharmacol. November 2015; 88(5):853-65.

Year Published: 2015

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