Peer-Reviewed Papers

Retro Drug Design: From Target Properties to Molecular Structures

GPCR Target: hMOR-CHO-K1

Authors: Wang, Y., et al

Journal: Journal of Chemical Information and Modeling 2022 62 (11), 2659-2669 DOI: 10.1021/acs.jcim.2c00123

Year Published: 2022

Field and laboratory perspectives on fentanyl and carfentanil decontamination

GPCR Target: hMOR-CHO-K1-Gαqi5

Authors: Lindén, P., et al.

Journal: Sci Rep 14, 25381 (2024). doi.org/10.1038/s41598-024-74594-z

Year Published: 2024

Discovery of N-substituted-2-oxoindolin benzoylhydrazines as c-MET/SMO modulators in EGFRi-resistant non-small cell lung cancer

GPCR Target: HEK293T-WT SMO membranes

Authors: Tomassi S, et al.

Journal: RSC Med Chem. 2024;16(1):77-97. doi:10.1039/d4md00553h

Year Published: 2024

Palmitic Acid Hydroxystearic Acids Activate GPR40, Which Is Involved in Their Beneficial Effects on Glucose Homeostasis

GPCR Target: GPR40 stable cell line, Cyclic AMP Assay

Authors: Syed, I., et al.

Journal: Cell Metab. 2018 Feb 6;27(2):419–427.e4. doi: 10.1016/j.cmet.2018.01.001

Year Published: 2018

Discovery of Novel and Selective GPR17 Antagonists as Pharmacological Tools for Developing New Therapeutic Strategies in Diabetes and Obesity

GPCR Target: 1321N1 GPR17 stable cell line (Catalog# Cr1525–3)

Authors: Zhu, H., et al.

Journal: European Journal of Medicinal Chemistry, Volume 295, 2025, 117794, doi: 10.1016/j.ejmech.2025.117794

Year Published: 2025

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