KiSS1-Derived Peptide GPCR Family Subtypes and Products

General Family Information

The KiSS1-derived peptide receptor is a G protein-coupled receptor (GPCR) involved in the regulation of puberty, fertility, and endocrine function. Agonist activity of the KiSS1 receptor results in the release of gonadotropin-releasing hormones. While full agonists have been identified for the KiSS1 receptor, no antagonists have currently been discovered.

Receptor FamilyReceptorSpeciesParentalStable Cell Lines Division-Arrested Cells Membranes
KiSS1-Derived PeptideKiSS1humanCHO dhfr-C1036DC1036MC1036
KiSS1ratCHO dhfr-C1036-1DC1036-1MC1036-1