Angiotensin GPCR Family Subtypes and Products

General Family Information

Angiotensin receptors are a family of G protein-coupled receptors (GPCRs) for the renin-angiotensin system, consisting of both angiotensin type 1 (AT1) receptors, and angiotensin type 2 (AT2) receptors. Angiotensin II (Ang II) functions as paracrine and autocrine hormones within the brain, heart, kidney, and blood vessels. AT1 and AT2 receptors play a role in blood pressure maintenance and glomerular filtration rate.

Receptor FamilyReceptorSpeciesParentalStable Cell Lines Division-Arrested Cells Membranes
AngiotensinAT1humanHEK293TH1417DH1417MH1417
AT1humanHEK293THA1417- BA1DHA1417- BA1MHA1417- BA1
AT1humanHEK293THA1417-BA2DHA1417-BA2MHA1417-BA2