Angiotensin GPCR Family Subtypes and Products
General Family Information
Angiotensin receptors are a family of G protein-coupled receptors (GPCRs) for the renin-angiotensin system, consisting of both angiotensin type 1 (AT1) receptors, and angiotensin type 2 (AT2) receptors. Angiotensin II (Ang II) functions as paracrine and autocrine hormones within the brain, heart, kidney, and blood vessels. AT1 and AT2 receptors play a role in blood pressure maintenance and glomerular filtration rate.
Receptor Family | Receptor | Species | Parental | Stable Cell Lines | Division-Arrested Cells | Membranes |
---|---|---|---|---|---|---|
Angiotensin | AT1 | human | HEK293T | H1417 | DH1417 | MH1417 |
AT1 | human | HEK293T | HA1417- BA1 | DHA1417- BA1 | MHA1417- BA1 | |
AT1 | human | HEK293T | HA1417-BA2 | DHA1417-BA2 | MHA1417-BA2 |