Adhesion GPCR Family Subtypes and Products
General Family Information
Adhesion receptors are a family of G protein-coupled receptors (GPCRs) that consists of 33 human protein receptors, a majority of which are orphan receptors. Work is being done to de-orphanize these. While ligands for many of these receptors remains unknown, ligand profiles and in vitro studies have shown a role for adhesion GPCRs in cell adhesion and migration, and the proper positioning of cells in various organ systems. There is growing evidence that also suggests a relationship in tumour cell metastasis.
Receptor Family | Receptor | Species | Parental | Stable Cell Lines | Division-Arrested Cells | Membranes |
---|---|---|---|---|---|---|
Adhesion Class GPCRs | GPR97 | human | HEK293T | C1396 | DC1396 | MC1396 |
GPR110 | human | HEK293T | C1378 | DC1378 | MC1378 |