The urotensin receptor is a G protein-coupled receptor (GPCR) found throughout the brain, blood vessels, and peripheral tissues, and is involved in cardiovascular issues, stress, and REM sleep, although the exact role is unknown. Activation of the urotensin receptor causes vasoconstriction, and has been suspected to be linked to cardiac hypertrophy. More research is required to discover selective urotensin receptor antagonists and further explore its biology.
