Prolactin-releasing peptide GPCR Family Subtypes and Products

The prolactin-releasing peptide (PrRP) receptor is a G protein-coupled receptor (GPCR) found within various regions of the brain, and once belonged to the orphan class of GPCRs. It is suspected that PrRP receptors have some function in breast cancer and human tumor development, and more recent students have shown that these receptors play a role in inflammatory and immune response for autoimmune disorders, such as arthritis and lupus. Research is being done into the role of PrRP receptors in recurrent miscarriages, preeclampsia, and peripartum cardiomyopathy, although exact etiology and mechanisms are currently unknown.