Glycoprotein hormone GPCR Family Subtypes and Products
General Family Information
Glycoprotein hormone receptors are a family of G protein-coupled receptors (GPCRs) comprised of three main hormone receptor subtypes: follitropin (FSH), lutropin (LH), and thyrotropin (TSH) hormone receptors. Monoclonal antibodies that activate the TSH receptor have already been produced as a treatment for Graves’ disease.
Receptor Family | Receptor | Species | Parental | Stable Cell Lines | Division-Arrested Cells | Membranes |
---|---|---|---|---|---|---|
Glycoprotein Hormone | TSH | human | HEK293T | H1177 | DH1177 | MH1177 |
TSH | rat | HEK293T | C1177-1 | DC1177-1 | MC1177-1 |