Glycoprotein hormone GPCR Family Subtypes and Products

General Family Information

Glycoprotein hormone receptors are a family of G protein-coupled receptors (GPCRs) comprised of three main hormone receptor subtypes: follitropin (FSH), lutropin (LH), and thyrotropin (TSH) hormone receptors. Monoclonal antibodies that activate the TSH receptor have already been produced as a treatment  for Graves’ disease.

Receptor FamilyReceptorSpeciesParentalStable Cell Lines Division-Arrested Cells Membranes
Glycoprotein HormoneTSHhumanHEK293TH1177DH1177MH1177
TSHratHEK293TC1177-1DC1177-1MC1177-1