MULTISCREEN™ MEMBRANE PREPARATION

HUMAN RECOMBINANT CB2 RECEPTOR

Product Information

Catalog Number:
MC1230-1a

Lot Number:
MC1230-1a-063014

Quantity:
1 vial (21.2mg/ml, 10mg)

Host cell:
CHO-K1

Transfection:
Expression vector containing full-length human CNR2 cDNA (GenBank Accession Number NM_001841) with FLAG tag sequence at N-terminus

Recommended Storage:
Liquid nitrogen upon receiving

Data Sheet

Background: Cannabinoid receptor 2 (CB2 or CNR2) is involved in cannabinoid- induced central nerve system effects. It could be a receptor for anandamide. The receptor is a potential therapeutic target in the treatment of various disease conditions, such as pain, multiple sclerosis, vascular disease, Parkinson’s disease, and other central nerve system disorders.

Figure 1. Receptor expression on cell surface measured by flow cytometry (FACS) using an anti-FLAG antibody. Thin line: parental cells; thick line: receptor-expressing cells.

References:

Mendizabal and Adler-Graschinsky (2003) Cannabinoid system as a potential target for drug development in the treatment of cardiovascular disease. Curr Vasc Pharmacol 1:301-313.

Gerard et al. (1990) Nucleotide sequence of a human cannabinoid receptor cDNA. Nucleic Acids Res 18:7142.

FOR RESEARCH USE ONLY.
All rights reserved. No part of this document may be reproduced in any form without prior permission in writing.

26219 Eden Landing Road Hayward, CA 94545 | (510) 887-0817 | info@multispaninc.com