MULTISCREEN™ DIVISION ARRESTED CELL LINE
HUMAN RECOMBINANT NTS1 RECEPTOR
1 vial (4 x 106) frozen cells
Expression vector containing full-length human NTSR1 cDNA (GenBank Accession Number NM_002531.2) with FLAG tag sequence at N-terminus
Liquid nitrogen upon receiving
Propagation Medium: DMEM, 10% FBS
Background: Human NTS1 is a 418 amino acid transmembrane protein in the neurotensin receptor family. It is primarily expressed in the central nervous system and in peripheral tissues. The neurotensin family plays an important role in a wide range of biological activities, such as hypotension, hyperglycemia, and regulation of vascular permeability. Recent studies have shown that NTS1 antagonists have great potential to become novel drugs for the treatment of neurodegenerative diseases, such as Parkinson’s disease.
Application: Functional assays