Cells, Membranes and Assay Kits

highly characterized reagents for screening and profiling

in multiple physiologically relevant assay formats

Stable cell lines

  • The best tools for studying all GPCR signaling-biases in one cell line
  • Minimally modified GPCRs and other targets directly selected in functional assays
  • Validated in MultiScreen™ assay kits in 384-well format
  • Holding the industry’s highest quality standards
  • Rigorous quality control ensures that 99% of the stable cell lines pass 2-month stability

Division-arrested cells

  • Convenient tools for cell-based high-throughput screening
  • Plate and read with ready-to-go assay conditions
  • Low-cost evaluation of a stable cell line or for limited number of compounds
  • Derived from well-characterized stable cell lines
  • Quality control performed in each lot for high performance functionality

Membranes preparations

  • Ideal for receptor binding assays
  • High receptor density
  • Prepared from Multispan’s stable cell lines for minimal lot-to-lot variability
  • Two-week turnaround for rapid delivery
  • Quality control by FACS for receptor surface expression

Summary Catalog

MultiScreen™ Calcium 1.0 No Wash Assay Kit

  • Preferred method in drug discovery for screening G protein coupled receptors (GPCR) and calcium channels
  • Optimized homogeneous fluorescence-based assay for detecting the intracellular calcium mobilization
  • The brightest calcium indicator, validated by MultiScreen™ stable cell lines
Assay Kits Graph 1

MultiScreen™ TR-FRET cAMP 1.0 No Wash Assay Kit

  • Homogenous TR-FRET assay based on the competition between HRP-labeled cAMP and non-labeled cAMP
  • A sensitive method for detecting adenylate cyclase activity in biochemical or cell-based assays
  • Validated by MultiScreen™ stable cell lines
Assay Kits Graph 2