GPCR Target: HEK293T cells overexpressing full-length GIPR or GLP-1R with an N-terminal FLAG tag were purchased from Multispan, Inc

Authors: Dewi Safitri, Matthew Harris, Abigail Pearce, Xianglin Huang, Matthew Rosa, Kerry Barkan, Edward Wills, Maria Marti-Solano, Matthew D. Falk, Graham Ladds

Company:

Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge CB2 1PD, United Kingdom; Pharmacology and Clinical Pharmacy Research Group, Institut Teknologi Bandung, Bandung

40132, Indonesia; Takeda Development Centre Americas Inc, San Diego, CA, USA

GPCR Target: Calcium assay, cAMP assay

Authors: Batran RZ, Gugnani KS, Maher TJ, Khedr MA.

Company: Chemistry of Natural Compounds Department, Pharmaceutical and Drug Industries Research Division, National Research Centre,Dokki, Giza, Egypt; Department of Pharmaceutical Sciences, MCPHS University, Boston, MA, USA.; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Helwan University, Ein Helwan, Cairo, Egypt

Journal: Bioorg Chem. 2021 Jun;111:104817

GPCR Target: Calcium assay

Authors: Aryal P, Syed I, Lee J, Patel R, Nelson AT, Siegel D, Saghatelian A, Kahn BB

Company: Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, USA; Clayton Foundation Laboratories for Peptide Biology, Salk Institute for Biological Studies, La Jolla, California, USA; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA

Journal: J Lipid Res. 2021;62:100108.

GPCR Target: CHO-K1-Gαqi5 Gal1R

Authors: Paulo A. De Oliveira, Estefanía Moreno, Nil Casajuana-Martin, Verònica Casadó-Anguera, Ning-Sheng Cai, Gisela Andrea Camacho-Hernandez, Hu Zhu, Alessandro Bonifazi, Matthew D. Hall, David Weinshenker, Amy Hauck Newman, Diomedes E. Logothetis, Vicent Casadó, Leigh D. Plant, Leonardo Pardo, Sergi Ferré

Company: Integrative Neurobiology Section, USA; Medicinal Chemistry Section, National Institute on Drug Abuse, Intramural Research Program, National Institutes of Health, Baltimore, MD, USA; Laboratory of Molecular Neuropharmacology, Department of Biochemistry and Molecular Biomedicine, Faculty of Biology and Institute of Biomedicine, University of Barcelona, Barcelona, Spain; Laboratory of Computational Medicine, Biostatistics Unit, Faculty of Medicine, Autonomous University of Barcelona, Bellaterra, Spain; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA; Department of Human Genetics, Emory University School of Medicine, Atlanta, GA, USA; Departments of Pharmaceutical Sciences, Chemistry and Chemical Biology and Center for Drug Discovery, School of Pharmacy at the Bouvé College of Health Sciences and College of Science, Northeastern University, Boston, MA, USA

Journal: Pharmacological Research, Volume 182, 2022, 106322,

GPCR Target: MOR GTPcS assays were conducted at Multispan Inc. (Hayward, CA) in membranes obtained from stably transfected CHO cell expressing the MOR receptor (CHO-K1 Multispan Inc., C1350-1a) using SPA beads (Perkin Elmer, RPNQ0001).

Authors: Beth Youngblood, Kevin Li, Donald R. Gehlert, Julio C. Medina and Neil Schwartz

Company: Epiodyne Inc., San Francisco, California and R2M Pharma Inc., South San Francisco, California

Journal: Journal of Pharmacology and Experimental Therapeutics August 2021, 378 (2) 133-145

GPCR Target: Antagonist potencies of test items at recombinant dog, rabbit, rat and mouse bradykinin B2 receptors stably expressed in HEK293 cells were determined at Multispan Inc 

Authors: Anne Lesage, François Marceau, Christoph Gibson, Brigitte Loenders, Werner Katzer, Horst-Dieter Ambrosi, Jörn Saupe, Alexander Faussner, Evangelia Pardali, Jochen Knolle

Company: Pharvaris GmbH., Zug, Switzerland; Département de Microbiologie, Infectiologie et Immunologie, Faculté de médecine, Université Laval, Québec, QC G1V 4G2, Canada; AnalytiCon Discovery GmbH, Potsdam, Germany; Pharvaris Netherlands B.V., Leiden, the Netherlands; Faculty of Medicine, Institute for Cardiovascular Prevention, Ludwig-Maximilians-University, Munich, Germany

Journal: International Immunopharmacology, Volume 105, April 2022, 108523