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GPCR Expression Technology

Multispan uses a proprietary technology to enable expression of GPCR proteins in mammalian cells at over a million molecule per cell surface. High expressing cells (HExTM) can be developed into single cell clones and be used as unique source of high quality GPCR proteins for variety of applications, including:
  • Antibody generation using antigens with natural epitopes at high expression level

  • Cell-based or membrane receptor binding assays to achieve high signal-to-noise ratio

  • Cell-based functional assays for hard-to-express GPCRs from all 3 structurally distinctive GPCR families, including Free Fatty Acid, Lysophospholipid, Prostanoid, Neuropeptide, Purinergic and Metabotropic Glutamate receptors.

  • Structural studies as high quality source of protein for crystallization for antibody generation and membranes for binding assays for high throughput screening.

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info@multispaninc.com
(510) 887- 0817 ext 101

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